Fig. 1

Microscopic features (H&E) of acral skin, correlating histological and dermatoscopic structures with the clinical appearance of pigmentation and melanocyte distribution. In macular benign melanocytic lesions, melanocytes are distributed along the surface furrows of acral skin (a), forming parallel lines that correspond histologically to the limitans ridges (b). In incipient acral lentiginous melanoma, melanocytic proliferation is more pronounced in the acrosyringium (c)