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Table 3 Logistic regression analysis for predictors of recurrence / distant metastasis

From: A high number of tumor deposits (≥ 4) is an isolated predictor of local recurrence and distant metastasis in non-metastatic colorectal cancer: a single center study

Variable

Recurrence/distant metastasis

Univariate

Multivariate

p-value

Crude OR(95% CI)

p-value

AORa (95% CI)

Age

0.2

0.98 (0.96–1.01)

0.4

0.99 (0.06–6.97)

Sex

0.7

1.2 (0.6–2.4)

-

-

Smoking

0.4

1.4 (0.69–2.84)

-

-

Alcohol

0.8

1.2 (0.55–2.26)

-

-

Family history

0.2

1.63 (0.78–3.46)

-

-

MSI: Loss-Intact

0.5

1.56 (0.39–6.15)

-

-

Mucinous histology

0.6

0.76 (0.39–1.99)

-

-

Signet ring

0.9

0.96 (0.08–10.95)

-

-

Tumor size

0.1

1.1 (0.98–1.26)

-

-

Lymph node status

0.03*

0.42 (0.19–0.91)

0.3

0.59 (0.24–1.49)

No. of lymph nodes

0.5

1.03 (0.94–1.14)

-

-

No. of LN extracted

0.4

0.95 (0.94–1.02)

-

-

No. of tumor deposits

0.04*

1.17 (1.007–1.37)

0.04*

1.17 (1.001–1.37)

LVI

0.07

2.18 (0.94–5.08)

-

-

PNI

0.9

1.04 (0.5–2.15)

-

-

Adjuvant therapy

0.02*

2.68 (1.22–5.92)

0.1

2.01 (0.79–5.12)

  1. AOR Adjusted Odds Ratio, BMI Body Mass Index, CI confidence interval, MSI Microsatellite instability, OR Odds Ratio, LVI lymphovascular invasion, PNI perineural invasion, AJCC American Joint Committee on cancer
  2. * p ≤ 0.05
  3. aAOR: Adjusted for (Age, lymph node status and adjuvant therapy) factors