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Fig. 6 | Surgical and Experimental Pathology

Fig. 6

From: The biliary tree musketeers: cholangiocarcinoma – one name for all, but at least three different diseases with distinct targets

Fig. 6

Example of extrahepatic cholangiocarcinoma with amplification for ERBB2 (HER2) gene (ERBB2/CEP17): ≥ 2. A) Score 3 + for ERBB2 (HER2) oncoprotein immunohistochemistry (IHC) pattern in biopsy specimen (following criteria used in the ToGA trial for scoring ERBB2 (HER2) oncoprotein expression by IHC in gastric and gastroesophageal junction adenocarcinoma; B) CEP17; C) ERBB2 (HER2) gene demonstrating amplification

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Surgical and Experimental Pathology

ISSN: 2520-8454

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