Fig. 15

Electron microscopy findings of right deltoid muscle biopsy of Patient 7. Muscle with areas of myofibrillar disruption with accumulation of mitochondria (yellow * in a, and b), subsarcolemal mitochondrial proliferation (yellow * in c, yellow arrow in d, and e) with abnormal mitochondrial paracrystalline inclusions (yellow arrow in f), nemaline bodies (red arrows in g, h, and i) (Transmission electron microscopy a 2,500x, b 2,000x, c 12,000x, d 5,000x, e 20,000x, f 50,000x, g 6,000x, h 10,000x, and i 100,000x)