Table 6 Comparison of sensitivity, specificity, PPV, NPV and diagnostic accuracy of the IAC Yokohama system for the diagnosis of malignant breast lesions in various studies
Groups | Wong S et al. (Wong et al. 2019) (n = 536) | Montezuma D et al. (Montezuma et al. 2019) (n = 755) | De Rosa F et al. (Rosa et al. 2020) (n = 1616) | Ahuja S et al. (Ahuja and Malviya 2021) (n = 224) | Present Study, 2023 (n = 321) | |
|---|---|---|---|---|---|---|
Group A (Only malignant category taken as positive) | Sensitivity | 75.4% | 68.7% | 82.2% | 79.2% | 82.1% |
Specificity | 100% | 100% | 97.8% | 100% | 100% | |
PPV | 100% | 100% | 98.8% | 100% | 100% | |
NPV | 80.7% | 87.7% | 71% | 90.9% | 93% | |
Diagnostic accuracy | 87.9% | 90.3% | 87% | 93.2% | 94.7% | |
Group B (Suspicious of malignancy and malignant taken as positive) | Sensitivity | 92% | 83.3% | 93.7% | 91.7% | 91.5% |
Specificity | 97.8% | 99.8% | 90.8% | 98.7% | 98.7% | |
PPV | 97.6% | 99.5% | 95.8% | 97.1% | 96.6% | |
NPV | 92.7% | 93% | 86.6% | 96.1% | 96.5% | |
Diagnostic accuracy | 95% | 94.7% | 92.8% | 96.4% | 96.5% | |
Group C (Atypical, suspicious and malignant category taken as positive) | Sensitivity | 98.9% | 98.3% | 98.9% | 97.2% | 95.7% |
Specificity | 62.1% | 54.8% | 56.3% | 86% | 90.2% | |
PPV | 71.7% | 49.2% | 30.5% | 77% | 81.9% | |
NPV | 98.3% | 98.6% | 95.1% | 98.5% | 97.9% | |
Diagnostic accuracy | 80.2% | 68.2% | 82.7% | 89.6% | 86.3% |